The Development of a diagnostic test for the detection of drugs in saliva using a disposable sample preparation Microfluidic cartridge

In this paper we report on the development of a diagnostic test for the detection of illegal drugs in saliva using a disposable micro-fluidic sample preparation cartridge which was fabricated using CO2 and excimer laser ablation of a PMMA substrate assembly. The detection method is by immunoassay sensing on a surface plasmon resonance (SPR) platform. Experimental results shows that the immunoassay detection of the two illegal drugs tested are very sensitive and have a linear range for cocaine and MDMA of 0,01 pg/ml – 1 ng/ml and 0,1 pg/ml – 100 ng/ml respectively.

Publication year: 2010
Authors: Sesay A M.1, Krühne U.2, Sonny S.3, Lund Olesen T.4, Virtanen V.5
Affiliations:

1, 3, 5 – University of Oulu, Finland
2 – Technical University of Denmark
4 – Danish Technological Institute, Denmark

ISBN 978-0-9798064-3-8

Published in: µTAS 2010 Groningen (2010), Verpoorte, S. et al.(Eds.), 1520-1522pp ISBN 978-0-9798064-3-8

MP-SPR KEYWORDS

diagnostic test disposable micro-fluidic sample preparation cartridge

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