Surface Plasmon Resonance on Nanoscale Organic Films

Surface Plasmon Resonance (SPR) has evolved over the past 20 years into a very versatile detection method, particularly in biosci- ence applications. Not only the scientific literature has greatly expanded, but also various commercial vendors of instrumentation, detection chips and reagents have emerged. In the scientific sphere the accent lies more and more on fabrication of nanostructures with interesting optical behavior (plasmonics), while in the R&D area there are many new miniaturization efforts and combination with other detection methods, such as electrochemistry and quartz crystal micro- balance QCM. The present chapter will focus on the latest developments in making functional biochemical coatings for SPR detection as well as review the basic theory behind the detection techniques.

Publication year: 2010
Authors: Willem M. Albers and Inger Vikholm-Lundin

VTT Technical Research Centre of Finland, Microtechnologies and Sensors, Molecular Sensors, P.O. Box 1300, FIN-33101 Tampere, Finland

Published in: Nano-Bio-Sensing, 1st ed, Chapter 4, Springer 2010


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